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What is SPE?

Solid phase extraction (SPE) is a method for rapid sample preparation in which a solid stationary phase, referred to as the sorbent, is typically packed into a well plate or syringe barrel and is used to selectively extract, concentrate, and purify target analytes prior to analysis by HPLC or GC.

SPE offers the following advantages:

Effective removal of contaminants
High recoveries of target analyte
Concentrate analytes and improve sensitivity

Get started by selecting the proper phase

1 -- Selecting the Proper Phase

SPE sorbents are most commonly categorized by the nature of their primary interaction or retention mechanism with the analyte of interest. More

2 -- Selecting the Proper Bed Mass

The sorbent bed mass determines the maximum amount of analyte that can be retained by the sorbent. More

3 -- Selecting the Proper Bed Volume

The bed volume of the sorbent determines the solvent volumes required in a SPE method. More

4 -- Sample Pre-Treatment for SPE

The sorbent bed mass determines the maximum amount of analyte that can be retained by the sorbent. More